Products for Research Use Only

LY3295668

CAT: 0013-GTR19203605-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203605-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY3295668 (AK-01) is a potent and highly selective Aurora A kinase inhibitor, exhibiting sub-nanomolar affinity (Ki = 0.8 nM) for Aurora A with over 1000-fold selectivity against Aurora B. This selectivity profile makes it a valuable chemical probe for investigating mitotic progression, centrosome maturation, and tumorigenesis in both cellular and animal models of cancer.
CAS Number
1919888-06-4
Product Name Alternative
LY 3295668, LY3295668, LY-3295668, Aurora A, AuroraKinase, Aurora Kinase, AK01, AK-01, AK 01
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.44% (May vary between batches)
Solubility
DMSO:90 mg/mL (183.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.74 mM)
Smiles
C[C@@H]1C[C@@] (Cc2nc (Nc3cc (C) [nH]n3) ccc2F) (CCN1Cc1cccc (Cl) c1F) C (O) =O
Molecular Formula
C24H26ClF2N5O2
Molecular Weight
489.95
Storage Conditions
-20°C
Notes
For research use only.