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P53 Activator 16

CAT: 0013-GTR19274802-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274802-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P53 Activator 16 (Compound JC16) is a p53 activator that shows selective cytotoxicity and pro-apoptotic (apoptosis) activity against cancer cells with the p53-Y220C mutation, while having minimal effects on wild-type or p53-null cells. It induces a conformational change in cellular p53-Y220C from mutant to wild-type, accompanied by transcriptional activation of p53 target genes, without increasing the overall level of p53 protein. p53 Activator 16 is useful for researching p53-mutant cancers.
Storage Conditions
-20°C
Notes
For research use only.

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