Products for Research Use Only
RegisterLogin

FGFR4-IN-24

CAT: 0013-GTR19274691-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19274691-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FGFR4-IN-24 is a selective irreversible covalent inhibitor of FGFR4 with an IC50 of 1.2 nM. It demonstrates significantly weaker activity against the other three FGFR family kinases (FGFR1-3) . FGFR4-IN-24 effectively inhibits the FGF19/FGFR4 signaling pathway, suppressing the proliferation of the HuH-7 hepatocellular carcinoma cell line (GI50= 17 nM) . In HuH-7 mouse xenograft models, FGFR4-IN-24 shows notable antitumor activity. This compound is applicable for hepatocellular carcinoma research.
CAS Number
3053546-73-6
Smiles
O=C (C=C) NC=1C=CC=CC1NC2=NC=3NC=C (C (=O) C4=CC (=CC=C4F) C (=O) NC5CC5) C3C=C2
Molecular Formula
C27H22FN5O3
Molecular Weight
483.5
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19274980-01FGFR-IN-24
GTR18102357FGFR4 Antibody
GTR18235505-01FGFR4 Antibody
GTR18225293FGFR4 Antibody
GTR19205883-01FGFR4-IN-4
GTR19185909-01FGFR4-IN-10
GTR17927182FGFR4 Antibody
GTR19250467-01FGFR4-IN-22
GTR18782936-01FGFR4 Antibody
GTR19262398-01FGFR4-IN-19

Alternative Products

CatalogName
HY-179381FGFR4-IN-24
400278-01FGFR4
70R-17296FGFR4 antibody
HY-145836FGFR4-IN-8
HY-115902FGFR4-IN-7
HY-147515FGFR4-IN-11
HY-129181FGFR4-IN-4
T209757-01FGFR4-IN-19
T206973-01FGFR4-IN-23
T37425-01FGFR4-IN-5

Popular Products