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Pt (II) -NHC complex 2C

CAT: 0013-GTR19274508-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274508-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pt (II) -NHC Complex 2C (Platinum (II) -N-Heterocyclic carbene complex 2C) (Compound 2C) is an N-heterocyclic carbene-based platinum (II) complex. This compound acts as an immunogenic cell death (ICD) inducer in liver cancer cells, triggering endoplasmic reticulum stress (ERS) and ROS production, which ultimately leads to the release of damage-associated molecular patterns (DAMPs) . Furthermore, it arrests the cell cycle in the S phase and significantly induces apoptosis. In mouse models, Pt (II) -NHC Complex 2C has demonstrated anticancer potential against liver cancer and activated immune cells in liver injury models.
CAS Number
3035433-94-1
Smiles
FC=1C=CC (=CC1) C2=C (C3=CC=C (F) C=C3) N ([C-2] (N2CC) =[Pt+4] ([I-]) ([I-]) [N]=4C=CC=CC4) CC
Molecular Formula
C24H23F2I2N3Pt
Molecular Weight
840.36
Storage Conditions
-20°C
Notes
For research use only.

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