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M464

CAT: 0013-GTR19274437-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274437-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M464 is a potent and orally active non-steroidal anti-inflammatory compound functioning as an NLRP3 inflammasome inhibitor. It works by preventing ASC oligomerization and decreasing ROS production, thereby inhibiting pyroptosis and blocking the expression of downstream Caspase-1 and the release of IL-1β. M464 demonstrates protective effects against acute lung and liver injury in mice and can be utilized in research on NLRP3-related inflammatory diseases.
Storage Conditions
-20°C
Notes
For research use only.

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