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PTPN2-IN-2

CAT: 0013-GTR19274363-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274363-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTPN2-IN-2 is a potent and orally bioavailable PTPN2 inhibitor with an IC50 of 7.05 nM, which enhances the IFN-γ signaling pathway. It also inhibits PTP1B with an IC50 of 9.88 nM. In the B16-OVA mouse model, PTPN2-IN-2 suppresses tumor growth and promotes the activation and infiltration of tumor immune cells. This compound is applicable in melanoma research.
CAS Number
3093350-44-5
Smiles
O=C (NC1CCCCCC1) C2=NC=C (N2) C=3C=C (F) C (=C (O) C3) N4CC (=O) NS4 (=O) =O
Molecular Formula
C19H22FN5O5S
Molecular Weight
451.47
Storage Conditions
-20°C
Notes
For research use only.

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