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EG01449

CAT: 0013-GTR19274308-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274308-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EG01449 is a quinoline-based neuropilin-1 (NRP1) antagonist with a Kd of 0.6 μM. It competitively inhibits the binding of VEGFA to NRP1 with an IC50 of 362 nM, preventing VEGFA-induced pain by inhibiting NRP1-dependent signaling and reducing sodium currents in sensory neurons. EG01449 can cross the blood-brain barrier, allowing for targeted actions within the central nervous system, and is utilized in pain research.
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-179350AEG01449

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