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XYDC2050

CAT: 0013-GTR19274287-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274287-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XYDC2050 (Compound 29) is a selective vasopressin V2 receptor (V2R) antagonist, with an IC50 of 27 nM and a Ki of 2.8 nM. It exhibits a Ki of 420.7 nM for V1R with a selectivity index of 162. XYDC2050 inhibits vasopressin-induced intracellular cyclic adenosine monophosphate (cAMP) accumulation with an IC50 of 12 nM. This compound can suppress kidney cyst growth, reduce kidney-to-body weight ratio, and decrease cyst area and cystic index, making it a candidate for autosomal dominant polycystic kidney disease (ADPKD) research.
Storage Conditions
-20°C
Notes
For research use only.

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