Products for Research Use Only

TTK-IN-5

CAT: 0013-GTR19274194-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274194-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TTK-IN-5 is an orally active and selective covalent threonine tyrosine kinase (TTK) inhibitor with an IC50 of 8.918 nM. It demonstrates antiproliferative activity against several cell lines, including MDA-MB-231, A2780, HCT116, HCC1569, and MKN1, with IC50 values of 0.113 μM, 0.476 μM, 3.136 μM, 3.649 μM, and 1.856 μM, respectively. In xenograft mouse models using A2780 and MDA-MB-231, TTK-IN-5 effectively inhibits tumor growth without significant toxicity. TTK-IN-5 is applicable in research on cancers such as breast and ovarian cancer.
Storage Conditions
-20°C
Notes
For research use only.

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