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GSK235

CAT: 0013-GTR19274184-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274184-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK235 is an orally active and selective allosteric inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), boasting pIC50 values of 8.45 and 7.59 for human and murine ERAP1, respectively. It demonstrates over 1000-fold selectivity against the highly homologous enzymes ERAP2 and IRAP. GSK235 modulates the immunopeptidome of cancer cells, enhancing their antigenicity, and is applicable in colorectal cancer and arthritis research.
Storage Conditions
-20°C
Notes
For research use only.

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