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NAE-IN-3

CAT: 0013-GTR19274163-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274163-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NAE-IN-3 (compound 1) is a potent and highly selective non-covalent competitive inhibitor of NEDD8-activating enzyme (NAE) with an IC50 of 0.8 μM. It inhibits NAE by blocking the ATP binding site and demonstrates selectivity over related E1 enzymes UAE and SAE. NAE-IN-3 is applicable for cancer research.
CAS Number
951950-33-7
Smiles
O=C (O) CNC (=O) CNC (=O) COC=1C=CC=2N=C3N (C (=O) C2C1) CCC3
Molecular Formula
C17H18N4O6
Molecular Weight
374.35
Storage Conditions
-20°C
Notes
For research use only.

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