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IMQT_020

CAT: 0013-GTR19274116-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274116-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IMQT_020 is a selective allosteric SLC1A5_var inhibitor. It disrupts the trimer assembly of SLC1A5_var, leading to a metabolic crisis in cancer cells and selectively inhibiting their growth. iMQT_020 reduces compensatory glutamine metabolism and oxidative phosphorylation, causing widespread metabolic disruption in cancer cells. It lowers GSH levels while increasing intracellular and mitochondrial ROS levels. Additionally, iMQT_020 induces apoptosis and ferroptosis and upregulates PD-L1 expression through epigenetic mechanisms. This compound is applicable in research on pancreatic, lung, and colon cancers.
CAS Number
2463893-46-9
Smiles
O=C1NC (=O) C2=CC (=CC=C2N1) C=3C=C (Cl) C (O) =CC3F
Molecular Formula
C14H8ClFN2O3
Molecular Weight
306.68
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-179557IMQT_020

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