Products for Research Use Only

MC-AcLys-GDEVD-PABC-Exatecan

CAT: 0013-GTR19274099-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274099-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MC-AcLys-GDEVD-PABC-Exatecan is a component of an antibody-drug conjugate (drug-linker conjugate for ADC) composed of an ADC linker (MC-AcLys-GDEVD-PABC) attached to the DNA topoisomerase I inhibitor, Exatecan. It operates by enhancing the release of small molecule drugs into the tumor microenvironment through a significant bystander effect, triggered by caspase-3-induced extracellular cleavage of the linker.
Storage Conditions
-20°C
Notes
For research use only.