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EPZ004777 formate

CAT: 0013-GTR19273969-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273969-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EPZ004777 formate is an effective and selective DOT1L inhibitor with an IC50 of 0.4 nM. It reduces levels of H3K79me2 and H3K79me1, significantly downregulating the expression of HOXA9 and MEIS1. This compound selectively inhibits the proliferation of MLL-rearranged cells and induces differentiation followed by apoptosis in leukemia cells, making it useful for leukemia research.
Storage Conditions
-20°C
Notes
For research use only.

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