Products for Research Use Only

Immunoproteasome-IN-2

CAT: 0013-GTR19273940-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273940-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Immunoproteasome-IN-2 is a selective immunoproteasome inhibitor with an IC50 of 232.3 nM for the LMP7 subunit and 9384.9 nM for the β5 subunit. It additionally displays inhibitory activity against LMP2 and MECL-1 subunits. In an arthritis mouse model, Immunoproteasome-IN-2 demonstrates anti-inflammatory effects and shows low hepatotoxicity and hematotoxicity in toxicology studies, linking its LMP7/β5 selectivity to reduced systemic toxicity. Immunoproteasome-IN-2 can be utilized in arthritis-related research.
Storage Conditions
-20°C
Notes
For research use only.