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NOSH-aspirin

CAT: 0013-GTR19273765-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273765-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NOSH-aspirin (NBS-1120) is an orally active hybrid molecule that releases nitric oxide and hydrogen sulfide. It inhibits the proliferation of pancreatic cancer cells and induces apoptosis. In a mouse model of pancreatic cancer, NOSH-aspirin suppresses tumor growth and inhibits NF-κB and FoxM1. Additionally, it alleviates motor deficits and dopaminergic neuronal degeneration in a rat model of Parkinson's disease and reduces neuroinflammation caused by the activation of microglia and astrocytes. NOSH-aspirin is useful for research in cancers such as pancreatic cancer and neurological disorders like Parkinson's disease.
CAS Number
1357362-67-4
Smiles
O=C (OC=1C=CC (=CC1) C=2SSC (=S) C2) C=3C=CC=CC3OC (=O) CCCON (=O) =O
Molecular Formula
C20H15NO7S3
Molecular Weight
477.52
Storage Conditions
-20°C
Notes
For research use only.

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