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SB772077B

CAT: 0013-GTR19273703-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273703-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB772077B is a ROCK inhibitor with anti-inflammatory properties. It boosts aqueous humor outflow (OF) by inhibiting the RhoA/ROCK signaling pathway. This compound significantly reduces mRNA levels of β-catenin and protein levels of fibrosis markers such as vinculin, fibronectin, collagen1 A, and vimentin. Additionally, SB772077B exhibits vasodilatory effects, lowering both pulmonary arterial and systemic blood pressure. It is useful for research on glaucoma and pulmonary arterial hypertension.
CAS Number
785774-34-7
Smiles
C (C) N1C=2C (N=C1C=3C (N) =NON3) =CN=CC2C (=O) N4CC[C@H] (N) C4
Molecular Formula
C15H18N8O2
Molecular Weight
342.36
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-123958SB772077B

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