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BI-9740

CAT: 0013-GTR19273685-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273685-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-9740 is an orally active, selective inhibitor of cathepsin C (CatC), displaying an IC50 of 0.6 nM in mice and 2.6 nM in rats. It inhibits the production of active neutrophil elastase and also reduces neutrophil elastase and cathepsin G activity in rat bone marrow, thereby alleviating pathological damage in heart transplants, shortening recovery time, and enhancing left ventricular function. BI-9740 is applicable for research related to organ transplantation.
CAS Number
1628596-25-7
Smiles
CN1C=2C (=CC=C (C2) C3=CC (F) =C (C[C@H] (NC (=O) [C@@H]4[C@@]5 (C[C@] (N4) (CC5) [H]) [H]) C#N) C=C3) CC1=O
Molecular Formula
C25H25FN4O2
Molecular Weight
432.5
Storage Conditions
-20°C
Notes
For research use only.

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