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PFKFB4-IN-1

CAT: 0013-GTR19273599-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273599-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PFKFB4-IN-1 is a potent and selective ATP-competitive inhibitor of PFKFB4 (IC50 = 4.50 μM) that reduces intracellular PFKFB4 protein levels. It exhibits over 12-fold selectivity for PFKFB1/4 and PFKFB3/4 isoforms. PFKFB4-IN-1 inhibits cancer cell proliferation, induces apoptosis, and suppresses cell migration. It also hinders tumor growth in MDA-MB-231 xenograft mouse models. PFKFB4-IN-1 is applicable for studies related to breast cancer, lung cancer, and liver cancer.
CAS Number
2664831-55-2
Smiles
O=N (=O) C=1OC (C=NNC2=CC=C (C3=NON=C32) N (=O) =O) =CC1
Molecular Formula
C11H6N6O6
Molecular Weight
318.21
Storage Conditions
-20°C
Notes
For research use only.

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