Products for Research Use Only

RPR107393

CAT: 0013-GTR19274435-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274435-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RPR107393 is an orally active and selective inhibitor of squalene synthase (SQS) . It inhibits squalene synthase in rat liver microsomes with an IC50 of 0.8 nM. By increasing cellular farnesol and its derivatives, RPR107393 suppresses fatty acid biosynthesis, thereby reducing triglyceride synthesis. It also lowers plasma cholesterol in rats and marmosets. RPR107393 is applicable in research related to metabolic diseases, such as hypercholesterolemia, hypertriglyceridemia, and atherosclerosis.
CAS Number
190841-57-7
Smiles
OC1 (CN2CCC1CC2) C3=CC=C (C4=CC=C5N=CC=CC5=C4) C=C3.Cl.Cl
Molecular Formula
C22H24Cl2N2O
Molecular Weight
403.35
Storage Conditions
-20°C
Notes
For research use only.