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AC-340

CAT: 0013-GTR19273902-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273902-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC-340 is a potent hybrid molecule functioning as a VDR agonist and HDAC inhibitor. It can significantly induce the expression of VDR target genes such as CYP24A1, with a selectivity for HDAC2 approximately 10 times greater than for HDAC6 (IC50= 0.37 μM) . By causing extensive protein hyperacetylation, such as that of tubulin and H3K9/K27, AC-340 enhances VDR superagonism, resulting in increased acetylation levels of H3K27 on VDR target genes. AC-340 is applicable in research related to melanoma.
Storage Conditions
-20°C
Notes
For research use only.

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