Products for Research Use Only

LATS-IN-2

CAT: 0013-GTR19273891-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273891-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LATS-IN-2 is a potent inhibitor of LATS, demonstrating significant inhibitory activity against LATS1 with an IC50 value of 1.3 nM. By inhibiting LATS kinase activity, LATS-IN-2 reduces the phosphorylation of YAP. Additionally, LATS-IN-2 increases the thickness of mouse epidermis and can be used in research on ocular diseases, such as limbal stem cell deficiency and corneal endothelial dysfunction.
CAS Number
2248728-49-4
Smiles
N=1C=CC2=C (N=C (N=C2NC3 (C) CC3) C4=CNN=C4C) C1
Molecular Formula
C15H16N6
Molecular Weight
280.34
Storage Conditions
-20°C
Notes
For research use only.