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G9a-IN-4

CAT: 0013-GTR19273491-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273491-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
G9a-IN-4 is a specific inhibitor of G9a with an IC50 of 32 nM. It exhibits high selectivity against other tested lysine/arginine methyltransferases. G9a-IN-4 shows enhanced enzymatic activity and demonstrates stronger antiproliferative effects on all tested cancer cell lines. It significantly inhibits H3K9me2 levels and induces autophagy via ROS generation, leading to apoptosis and G0/G1 cell cycle arrest in CT26 colon cancer cells. G9a-IN-4 is applicable for colon cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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