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FPR2 agonist 5

CAT: 0013-GTR19273450-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273450-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FPR2 agonist 5 is a selective agonist of formyl peptide receptor 2 (FPR2) . It induces Ca2+ mobilization in HL60 cells transfected with FPR2, demonstrating an EC50 value of 1.2 μM, and causes FPR2 desensitization with an IC50 of 0.32 μM. Additionally, FPR2 agonist 5 exhibits neuroprotective effects by reducing LDH release, NO production, and the levels of IL-1β, IL-6, IL-33, and IL-10 in LPS-induced primary microglial cells from mice. It is utilized in research related to neuroinflammatory and inflammatory diseases.
Storage Conditions
-20°C
Notes
For research use only.

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