PI3KC2γ-IN-1

CAT: 0013-GTR19273436-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19273436-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PI3KC2γ-IN-1 (Compound 23) is an orally active and selective inhibitor of PI3KC2γ with an IC50 of 4 nM. It downregulates the Akt2-glycogen synthase (GS) signaling pathway, ultimately inhibiting the conversion of glucose to glycogen and reducing excessive glycogen accumulation in the liver. PI3KC2γ-IN-1 significantly inhibits insulin-induced accumulation of PI (3,4) P2 in primary hepatocytes and HepG2 liver cancer cells. It is useful for researching glycogen storage diseases (GSDs) .

Storage Conditions

-20°C

Notes

For research use only.

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PI3KC2γ-IN-1

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