Products for Research Use Only

MyD88-IN-3

CAT: 0013-GTR19273397-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273397-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MyD88-IN-3 is an orally active, selective MyD88 inhibitor that specifically targets the TIR domain of MyD88 (KD= 28.5 μM) . It prevents MyD88 self-aggregation and its interaction with TLRs, thereby suppressing the activation of the MAPK and NF-κB pathways. MyD88-IN-3 exhibits significant anti-inflammatory effects and effectively alleviates symptoms of acute lung injury in CLP (cecal ligation and puncture) and LPS (lipopolysaccharide) -induced ALI models. This compound is valuable for ALI research.
Storage Conditions
-20°C
Notes
For research use only.