Products for Research Use Only

SHY-855

CAT: 0013-GTR19273392-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273392-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHY-855 is a pan-RAS inhibitor that effectively blocks the binding of K-Ras protein and other members of the RAS small GTPase superfamily, with an IC50 value ranging from 0.3 to 5 μM. It efficiently inhibits the phosphorylation of downstream targets such as MEK, ERK1/2, and AKT. Additionally, SHY-855 prevents the formation of Ras-GTP active complexes. This compound can be utilized in research related to pancreatic cancer and non-small cell lung cancer.
CAS Number
2446485-15-8
Smiles
ClC=1C (OC) =CC=CC1C=2SC3=NC (=NC (NCCOC) =C3C2C=4C=CC=CC4) C5=NC=CN5C
Molecular Formula
C26H24ClN5O2S
Molecular Weight
506.02
Storage Conditions
-20°C
Notes
For research use only.