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TLR9 antagonist 1

CAT: 0013-GTR19273154-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273154-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR9 antagonist1 (Compound 38) is a selective TLR9 inhibitor with an IC50 of 0.1 nM for hTLR9, demonstrating superior antagonistic activity compared to hTLR2/4/5/7/8. This compound exacerbates disease symptoms in mouse models of systemic lupus erythematosus (SLE) and raises levels of anti-dsDNA and anti-Sm antibodies. TLR9 antagonist1 is applicable in research on inflammatory and immune diseases such as lupus and arthritis.
Storage Conditions
-20°C
Notes
For research use only.

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