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MM927

CAT: 0013-GTR19273058-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273058-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MM927 is a potent NVL inhibitor with an IC50 value of 0.053 μM. It disrupts the biosynthesis of the 60S ribosomal subunit within the nucleolus, induces halfmer polysome formation, causes cell cycle arrest at the G1/S and G2/M phases, and triggers apoptosis (apoptosis) . Demonstrating antitumor activity in both MOLM-13 acute myeloid leukemia (AML) and HCT116 colorectal cancer (CRC) xenograft models, MM927 can be utilized for studying AML and CRC cancers.
CAS Number
3065567-21-4
Smiles
O=C1OC2=CC=C (C=C2N1C) C (=O) NC3=CC=C4C (SC5=CC (F) =CC=C5C (=O) N4CC#CC) =C3
Molecular Formula
C26H18FN3O4S
Molecular Weight
487.51
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-175783-01MM927

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