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Org 274178-0

CAT: 0013-GTR19273051-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273051-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Org 274178-0 is a selective antagonist of the thyroid-stimulating hormone receptor (TSHR), with a pIC50 value of 5.03 for TSHR. It inhibits the activation of the cAMP and phospholipase C (PLC) signaling pathways mediated by thyroid-stimulating hormone (TSH) and TSH receptor-stimulating immunoglobulins (TSIs) . Org 274178-0 shows potential for research in Graves' disease and Graves' ophthalmopathy.
Storage Conditions
-20°C
Notes
For research use only.

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