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CD28-IN-1

CAT: 0013-GTR19273047-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273047-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD28-IN-1 (Compound 19MS-5) is a CD28 inhibitor with a dissociation constant (KD) of 12.48 μM. It demonstrates excellent binding affinity to CD28, effectively hindering the CD28-B7 interaction. CD28-IN-1 suppresses CD28-driven immune activation and reduces cytokine production (IFN-γ, IL-2, and TNF-α) in primary human T cells co-cultured with tumor spheroids and human epithelial tissues. This compound is suitable for use in tumor immunology research.
CAS Number
1465291-19-3
Smiles
O=C (OCCC=1C (=NNC1C) C) C2=CC=CC3=C2OC (=O) N3C
Molecular Formula
C16H17N3O4
Molecular Weight
315.33
Storage Conditions
-20°C
Notes
For research use only.

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