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Factor XI-IN-2

CAT: 0013-GTR19273023-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273023-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Factor XI-IN-2 is a Factor XI activation inhibitor with an IC50 of 20 nM. It does not directly inhibit the enzymatic activity of FXIa but specifically binds to the FXI zymogen, allosterically inhibiting the activation process of the FXI zymogen by FXIIa. Factor XI-IN-2 suppresses thrombosis in a rabbit arteriovenous (AV) shunt thrombosis model and can be used in antithrombotic research.
CAS Number
2563884-39-7
Smiles
O=C (C1=NC=2C=CC (OCC=3C=CC=4SN=NC4C3) =CC2C (=C1) C (=O) N5CCCCC5) N6CCC (N7N=CC=C7) CC6
Molecular Formula
C31H31N7O3S
Molecular Weight
581.7
Storage Conditions
-20°C
Notes
For research use only.

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