Products for Research Use Only

SARM1-IN-7

CAT: 0013-GTR19272956-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272956-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SARM1-IN-7 is a potent, orally active inhibitor of SARM1, targeting its active site (orthosteric) . This compound persistently enhances SARM1's enzymatic activity, leading to exacerbated NAD depletion at suboptimal concentrations. In both cell and mouse models with activated SARM1, SARM1-IN-7 exhibits dual effects: high doses provide cell/neuron protection, whereas low doses intensify cell/neuron damage. SARM1-IN-7 is applicable in studies of axonal degeneration.
Storage Conditions
-20°C
Notes
For research use only.