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TJU103

CAT: 0013-GTR19272916-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272916-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TJU103 is a CD4 inhibitor that impedes the functionality of CD4 during activation, thereby suppressing autoreactive CD4+ T cells. In a mouse model of experimental autoimmune encephalomyelitis (EAE), TJU103 reduces monocyte infiltration in brain and spinal tissues. It downregulates Th1 and Th2 cytokine levels against proteolipid protein epitope 139-151 (PLPe) and exhibits inhibitory effects both after EAE symptom onset and subsequent antigen stimulation. TJU103 is applicable in research on autoimmune diseases such as EAE and multiple sclerosis (MS) .
CAS Number
10245-44-0
Smiles
O=C (NN=CC1=CNC=2C=CC=CC12) C=3C=CN=CC3
Molecular Formula
C15H12N4O
Molecular Weight
264.29
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-W795993TJU103

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