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STAT3-IN-46

CAT: 0013-GTR19272899-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272899-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STAT3-IN-46 is a selective, orally active inhibitor of the signal transducer and activator of transcription 3 (STAT3), with a KD value of 323.3 nM. It binds directly to the SH2 domain of STAT3, inhibiting the IL-6/JAK/STAT3 signaling pathway with an IC50 value of 0.87 μM, and decreases levels of c-Myc and Bcl-2. STAT3-IN-46 is applicable in cancer research, including studies on triple-negative breast cancer.
Storage Conditions
-20°C
Notes
For research use only.

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