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NB-3

CAT: 0013-GTR19272842-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272842-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NB-3 is an inhibitor of SARM1, the NAD+ hydrolase. NB-3 can block the hydrolysis process of NAD+ and form a covalent bond with the reaction product adenosine diphosphate ribose (ADPR) . The small-molecule ADPR adduct formed by the binding of NB-3 and ADPR shows excellent activity and exerts neuroprotective effects in nerve injury-related scenarios.
CAS Number
3109123-46-5
Smiles
[C@H] (N (C (NCC (F) (F) F) =O) C) (C) C=1C=CN=CC1
Molecular Formula
C11H14F3N3O
Molecular Weight
261.24
Storage Conditions
-20°C
Notes
For research use only.

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