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FXR agonist 15

CAT: 0013-GTR19274155-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274155-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXR agonist15 is a selective, potent, orally active farnesoid X receptor (FXR) agonist with an EC50 of 0.76 μM. It does not significantly activate other nuclear receptors such as LXRα/β, PXR, PPARα/β/γ, and THR-β, with EC50 values exceeding 10 μM for each. FXR agonist15 is effective in alleviating symptoms like steatosis, lobular inflammation, hepatocellular ballooning, and liver fibrosis. It is applicable in research studies related to non-alcoholic steatohepatitis (NASH) .
CAS Number
2991276-14-1
Smiles
O=C (O) COC=1C=CC (=CC1F) C2=CC=C (C=C2) N (CC (C) C) S (=O) (=O) C=3C (Cl) =CC=CC3Cl
Molecular Formula
C24H22Cl2FNO5S
Molecular Weight
526.4
Storage Conditions
-20°C
Notes
For research use only.

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