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FXR agonist 3

CAT: 0013-GTR19220734-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19220734-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXR agonist 3 is a potent small molecule that activates the Farnesoid X Receptor (FXR), demonstrating anti-NASH, antifibrotic, and hepatoprotective effects. It inhibits key fibrotic markers like COL1A1 (IC50 = 8.19 μM) in vitro and ameliorates liver injury in CDAHFD and BDL rodent models in vivo.
Field of Research
Immunology & Inflammation; Pharmacology & Drug Discovery, Metabolism Research
Purity
95.04% (May vary between batches)
Solubility
DMSO:200 mg/mL (383.79 mM)
Smiles
COC1=CC2=C (C=C1OC) CC[N+]3=C2C=C4C (C (OCC5=CC=CC (C) =C5) =C (OC) C=C4) =C3.[Br-]
Molecular Formula
C28H28BrNO4
Molecular Weight
521.12
Storage Conditions
-20°C
Notes
For research use only.

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