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KMR-206

CAT: 0013-GTR19273316-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273316-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KMR-206 is a potent and selective PARP7 inhibitor with an IC50 of 13.7 nM. It enhances the expression of STAT1 and phosphorylated Tyr701 site STAT1 (pSTAT1) . KMR-206 induces STING degradation and elevates type I IFN receptor levels, showing anticancer activity against lung adenocarcinoma and is applicable in colon cancer research.
CAS Number
2992741-10-1
Smiles
N#CC1=CN=C (C=C1) N2CCN (C (=O) C3=CC (=CC=C3F) CC4=NNC (=O) C=5C=CC (C#CC) =CC54) CC2
Molecular Formula
C29H23FN6O2
Molecular Weight
506.54
Storage Conditions
-20°C
Notes
For research use only.

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