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USP30-IN-20

CAT: 0013-GTR19273143-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273143-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP30-IN-20 is an orally active USP30 inhibitor with a Kd of 1.61 μM and an IC50 of 12.8 μM. It induces ferroptosis by promoting the ubiquitination-mediated degradation of GPX4. This compound inhibits the proliferation, migration, and invasion of prostate cancer cells and induces G0/G1 phase arrest while increasing ROS levels. In a mouse xenograft model with PC3 cells, USP30-IN-20 demonstrates significant antitumor activity. It is applicable for advanced prostate cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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