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Coccinine

CAT: 0013-GTR19266319-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19266319-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coccinine ((-) -Coccinine) is a weak inhibitor of SERT with an IC50 of 196.3 μM and a Ki of 106.8 μM, and P-gp with an IC50 of 0.96 mM. It demonstrates significant antitumor activity against various cancer cell lines, including breast cancer (MCF7, Hs578T, MDA-MB-231), colon cancer (HCT-15), and lung cancer (A549) . Additionally, Coccinine is applicable in research involving tumors and neurological disorders.
CAS Number
485-57-4
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O (C) [C@@H]1C=C2[C@@]3 (C=4C (C[N@@] (C3) [C@]2 (C[C@@H]1O) [H]) =CC5=C (C4) OCO5) [H]
Molecular Formula
C17H19NO4
Molecular Weight
301.34
Storage Conditions
-20°C
Notes
For research use only.

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