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Mycothiazole

CAT: 0013-GTR19265920-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265920-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mycothiazole is an inhibitor of mitochondrial electron transport chain (ETC) complex I. It exhibits cytotoxicity in cancer cells Huh7 (IC50 of 55.8 μM), U87, and MCF7. In Huh7 cells, Mycothiazole induces apoptosis (apoptosis) . Additionally, Mycothiazole extends the lifespan of C. elegans by modulating transcription factors ATFS-1 and HSF1, which are associated with the unfolded protein response (UPR) and heat shock response (HSR) .
CAS Number
114582-75-1
Field of Research
Metabolism Research
Smiles
C ([C@H] (C/C=C\C (CCNC (OC) =O) =C) O) (C) (C) C1=NC (C/C=C\CC=C) =CS1
Molecular Formula
C22H32N2O3S
Molecular Weight
404.57
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-N12887Mycothiazole
sc-5075718-OAc-mycothiazole

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