Sitostanol

CAT: 0804-HY-113494-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-113494-01Size:5 mg
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Description
Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma[1][2][3][4].
CAS Number
[83-45-4]
Product Name Alternative
Stigmastanol; 24α-Ethyl cholestanol
UNSPSC
12352211
Hazard Statement
H301+H311+H331
Target
Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/Stigmastanol.html
Purity
99.0
Solubility
DMSO : < 1 mg/mL|Ethanol : 5 mg/mL (ultrasonic)
Smiles
CC[C@H](CC[C@@H](C)[C@]1([H])[C@]2(C)[C@](CC1)([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2)C(C)C
Molecular Formula
C29H52O
Molecular Weight
416.72
Precautions
H301+H311+H331
References & Citations
[1]Pinhas H, et al. 6-amino derivatives of stigmastanol and cholestanol. J Med Chem. 1971;14 (11) :1048-1049.|[2]Tanemossu SA, et al. Rare biscoumarin derivatives and flavonoids from Hypericum riparium. Phytochemistry. 2014;105:171-177.|[3]Nascimento EBM, et al. In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes. Eur J Nutr. 2020 Aug;59 (5) :2039-2045.|[4]Brüll F, et al. Beneficial effects of sitostanol on the attenuated immune function in asthma patients: results of an in vitro approach. PLoS One. 2012;7 (10) :e46895.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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