Beta-Sitosterol (Standard)

CAT: 0804-HY-N0171R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0171R-01Size:5 mg
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Description
Beta-Sitosterol (Standard) is the analytical standard of Beta-Sitosterol. This product is intended for research and analytical applications. Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc.
CAS Number
[83-46-5]
Product Name Alternative
β-Sitosterol (Standard) ; 22,23-Dihydrostigmasterol (Standard) )
UNSPSC
12352211
Hazard Statement
H315-H319-H320
Target
Apoptosis; Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/beta-sitosterol-purity-80-standard.html
Purity
98.18
Smiles
CC[C@@H](C(C)C)CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Formula
C29H50O
Molecular Weight
414.71
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Citation 01
Cytotechnology. 2025 Apr;77 (2) :76.|Naunyn Schmiedebergs Arch Pharmacol. 2025 Oct 2.|Evid Based Complement Alternat Med. 2020 Apr 29;2020:2760979.|J Ethnopharmacol. 2025 Sep 9;355 (Pt A) :120590.|Mol Med Rep. 2025 Apr;31 (4) :95.|Patent. US20240209361A1.|Sci Rep. 2025 Jul 11;15 (1) :25045.

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