Products for Research Use Only

Artobiloxanthone

CAT: 0013-GTR19265997-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265997-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Artobiloxanthone (Compound AA3) exhibits antitumor activity, particularly against oral squamous cell carcinoma (OSCC) . It inhibits the Akt/mTOR and STAT3 pathways, thereby suppressing the proliferation of SAS and T.Tn cells with IC50 values of 11 and 22 μM, respectively, as well as cancer cell migration. Artobiloxanthone induces cell apoptosis in OSCC by activating caspase3/9 and causes cell cycle arrest at the S phase.
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C25H22O7
Storage Conditions
-20°C
Notes
For research use only.

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