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USP10-IN-4

CAT: 0013-GTR19265457-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265457-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP10-IN-4 is a potent inhibitor of ubiquitin-specific protease 10 (USP10), with an IC50 of 10.87 μM and a Kd of 365 nM. It effectively inhibits USP10-mediated proteasomal degradation of downstream proteins YAP and p53, leading to the downregulation of CDK4 in the p53 signaling pathway. USP10-IN-4 promotes apoptosis in liver cancer cells (apoptosis) and inhibits the initiation and progression of liver cancer. It is applicable in the study of hepatocellular carcinoma (HCC) .
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.

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