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JAK2-IN-13

CAT: 0013-GTR19264251-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264251-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK2-IN-13 is a potent and orally active JAK2 inhibitor with an IC50 of 54.7 nM. It downregulates the expression of p-STAT3 and p-STAT5 and exhibits good bioavailability. JAK2-IN-13 effectively suppresses recombinant human erythropoietin-induced extramedullary erythropoiesis as well as polycythemia vera. It is used in the study of myeloproliferative neoplasms.
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.

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