LYG-202

• Description :

  LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. LYG-202 inhibits VEGF-stimulated HUVEC migration and tube formation. LYG-202 induces cancer cell apoptosis[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/lyg-202.html

• Purity :

  99.04

• Solubility :

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(OCCCCN4CCN(C)CC4)=CC(O)=C13

• Molecular Formula :

  C25H30N2O5

• Molecular Weight :

  438.52

• Precautions :

  H301

• References & Citations :

  [1]Chen Y, et al. LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. J Pharmacol Sci. 2010;112 (1) :37-45.|[2]Zhao Y, et al. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells. Apoptosis. 2015 Sep;20 (9) :1253-69.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1175077-25-4]