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DPC 684

CAT: 0013-GTR19264058-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264058-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.
CAS Number
284661-73-0
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
[C@@H] ([C@@H] (CN (S (=O) (=O) C1=CC=C (N) C=C1) CC (C) C) O) (CC2=CC=CC=C2) NC ([C@@H] (NC (CNCC3=CC (F) =CC=C3) =O) [C@] (C) (C) C) =O
Molecular Formula
C35H48FN5O5S
Molecular Weight
669.85
Storage Conditions
-20°C
Notes
For research use only.

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