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3′,5′-DiOA-dC

CAT: 0013-GTR19264019-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264019-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3’,5’-DiOA-dC is a hydrophobic nucleotide lipid and acts as a ligand for the STING agonist c-di-GMP (CDG) . It can assemble with CDG to form stable cyclic dinucleotide nanoparticles through molecular recognition-driven supramolecular forces. This interaction reduces tumor weight and volume while increasing the levels of CD8 T cells, neutrophils, and NK cells in the tumor microenvironment. Additionally, 3’,5’-DiOA-dC enhances TNF-α and IFN-γ levels in a mouse melanoma model.
Field of Research
Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.

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